IkBalpha Antibody

IkBalpha Antibodyis available at Gentaur for Next week Delivery.

Description: IkB-alpha protein is a NF-kB inhibitory protein. It binds NF-kB and retains the complex in the cytoplasm, thereby preventing it from entering into nucleus and functioning as a transcription factor. Upon receiving a variety of signals, IkB-alpha undergoes phosphorylation at serine residues by an ubiquitin-dependent protein kinases and finally degraded by the proteasome. Free NF-kB then binds DNA and affects gene expression.

Immunogen Sequence:E. coli expressed mouse IkBa

Target Alternative Name:NFKBIA, IKBA, MAD3,MAD-3, IkappaBalpha, I-kappa-B-alpha, # NFKBI, IkB-alpha, NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkappaBalpha; IkB-alpha

Species Reactivities:Mouse

Tag Line:/

Formulation:100 µg (0.2 mg/ml) affinity-purified rabbit anti-IkB-alpha polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, and 0.02% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blot (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Cross-reactivity to IkB-alpha of other species has not been determined.

Handling:The antibody solution should be gently mixed before use.