IGF-BP3 Antibody

IGF-BP3 Antibodyis available at Gentaur for Next week Delivery.

Description: Human IGF-BP3, also known as growth-hormone-dependant binding protein, is a 28.9 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals. In addition to its ability to modulate the activity of IGF-I and IGF-2, IGF-BP3 also exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF.

Immunogen Sequence:E. coli expressed human IGF-BP3 (Cat.# 4720-25)

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Species Reactivities:Human

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

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Application And Usages:Western blotting (2-6 µg/ml). However, the optimal conditions should be determined individually. Recombinant human IGFBP-3 (Cat.# 4720-25) can be used as a positive control. Other applications have not been determined.

Handling:The antibody solution should be gently mixed before use.