GSK-3b Antibody

GSK-3b Antibodyis available at Gentaur for Next week Delivery.

Description: Glycogen synthase kinase 3 (GSK-3) is a serine/threonine protein kinase that has been implicated in the regulation of cell fate and in the Wnt signaling pathway. GSK-3 plays an important role in the PI3 kinase and Akt mediated cell survival pathways, and its activity can be inhibited by Akt-mediated phosphorylation at Ser21 of GSK-3α and Ser9 of GSK-3β. GSK-3 has also been implicated in alzheimer’s disease. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK-3.

Immunogen Sequence:Active recombinant human GSK-3β

Target Alternative Name:EC 2.7.11.26, GSK-3beta , glycogen synthase kinase 3 beta

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.2 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry

Positive Control:/

Application And Usages:Western blot analysis (0.5-4 µg/ml), in Immunohistochemistry (10-30 µg/ml). However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.