Gai2 Antibody

Gai2 Antibodyis available at Gentaur for Next week Delivery.

Description: Gαi2 is a 40-41 kDa alpha-subunit of heterotrimeric protein that shares sequence homology with Gαi3 and Gαi1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gαi2 is expressed widely in tissues and cell lines. Activation of PLC-β by Gαi-coupled receptors is the result of release of Gβg subunits from Gαi. Gαi2 regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.

Immunogen Sequence:Synthetic peptide surrounding amino acid 229 of human Gai2

Target Alternative Name:guanine nucleotide binding protein G, GNAI2B, guanine nucleotide binding protein

Species Reactivities:Human

Tag Line:/

Formulation:30 µg (0.5 mg/ml) affinity-purified rabbit anti-Gαi2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunoprecipitation

Positive Control:/

Application And Usages:Western blot (at 0.5-4 µg/ml) and immunoprecipitation. However, the optimal conditions should be determined individually.

Handling:The antibody solution should be gently mixed before use.