FKBP12 Antibody

FKBP12 Antibodyis available at Gentaur for Next week Delivery.

Description: FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.

Immunogen Sequence:Synthetic peptide surrounding amino acid 10 of mouse FKBP12

Target Alternative Name:FKBP1A , FKBP1 , FKBP12

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:30 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot, Immunohistochemistry/Immunoprecipitation

Positive Control:/

Application And Usages:Western blot (0.5-4 µg/ml), immunoprecipitation (2-10 µg/ml) and Immunohistochemistry (2-10 µg/ml). However, the optimal conditions should be determined individually. The antibody detects 12 kDa FKBP12 protein in samples from human, mouse, and rat origins.

Handling:The antibody solution should be gently mixed before use.