Ficolin-1 Antibody

Ficolin-1 Antibodyis available at Gentaur for Next week Delivery.

Description: Ficolin-1 also known as M-Ficolin is a pattern recognition molecule of the lectin complement activation pathway. It is expressed mostly in monocytes, nuetrophils and in type II alveolar epithelial cells. Ficolin-1 is detected on the surface of circulating monocytes but is not present in the plasma. Ficolin-1 has a 28 aa signal sequence, an N-terminal collagen domain and a C-terminal fibrinogen-like (FBG) domain that contain a calcium binding site and a potential N-glycosylation site.

Immunogen Sequence:Synthetic peptide surrounding amino acid 320 of rat Ficolin-1

Target Alternative Name:Flow cytometryN1 , Flow cytometryNM , ficolin 1

Species Reactivities:Human, mouse, rat

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Formulation:30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

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Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~33 kDa Ficolin-1 and a 37 kDa Ficolin-1 precursor in samples from human, mouse and rat origins. Reactivity to other species has not been tested.

Handling:The antibody solution should be gently mixed before use.