DPPIV (Mouse) Antibody

DPPIV (Mouse) Antibodyis available at Gentaur for Next week Delivery.

Description: Dipeptidyl peptidase-IV (DPPIV), also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.

Immunogen Sequence:Mouse myeloma cell line NS0-derived recombinant mouse DPPIV/CD26

Target Alternative Name:DPP4, DPP-4, ADABP, ADCP2, ADCP-2, CD26, CD-26, DPPIV, DPPIV, TP103, TP-103

Species Reactivities:Mouse

Tag Line:Polyclonal antibody to detect DPPIV in mouse samples

Formulation:0.2 mg/ml in PBS

Purification: Antigen affinity purified

Application:Western Blot, IHC

Positive Control:Western Blot, IHC

Application And Usages:WB: 0.1 µg/ml, IHC: 5-15 µg/ml

Handling:The antibody solution should be gently mixed before use.