DEDAF Antibody

DEDAF Antibodyis available at Gentaur for Next week Delivery.

Description: Cell death signal are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. A novel protein that interacts with DED of caspase-8 and -10, and FADD was recently identified and designated DEDAF (for DED associated factor). DEDAF is identical to the transcriptional repressor RYBP. DEDAF interacts with FADD and aμgments the formation of CD95/FADD/caspase-8 complexes at the cytoplasm. DEDAF also interacts with DED-containing DNA biding protein (DEDD) in the nucleus, indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.

Immunogen Sequence:Synthetic peptide surrounding amino acid 218 of human DEDAF

Target Alternative Name:DEDAF , YEAF1 , AAP1 , APAP-1, RYBP, RING1 and YY1-binding protein; Death effector domain-associated factor; DED-associated factor; YY1 and E4TF1-associated factor 1; Apoptin-associating protein 1; APAP-1

Species Reactivities:Human, mouse, rat

Tag Line:/

Formulation:100 µg (0.5 mg/ml) affinity purified rabbit anti-DEDAF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. A549 or HepG2 cell lysate can be used as a positive control. A 32 kDa band should be detected.

Handling:The antibody solution should be gently mixed before use.