Cleaved-Caspase-1 Antibody

Cleaved-Caspase-1 Antibodyis available at Gentaur for Next week Delivery.

Description: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. Cleaved-caspase-1 (D210) detects levels of fragment of activated Caspase-1 protein resulting from cleavage adjacent to D210.

Immunogen Sequence:Synthesized peptide derived from human Caspase-1 between Ser 129 - Asn 205

Target Alternative Name:CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, IL1BC, IL1BCE, CASP1

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect active form of Casepase-1 in Human

Formulation:50 µl purified antibody supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity purified rabbit IgG

Application:Western Blot, Immunohistochemistry, ELISA,

Positive Control:Western blot

Application And Usages:WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000

Handling:The antibody solution should be gently mixed before use.