CD86 Polyclonal Antibody

CD86 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.

Immunogen Sequence:KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human CD86.

Target Alternative Name:T-lymphocyte activation antigen CD86, Activation B7-2 antigen, B70, BU63, CTLA-4 counter-receptor B72, FUN-1, CD86, CD86, CD28LG2

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect LAG3 in human and mouse samples.

Formulation:PBS with 0.09% (W/V) sodium azide.

Purification: Protein A column, followed by peptide affinity purification.

Application:WB

Positive Control:WB

Application And Usages:WB~~1:1000

Handling:The antibody solution should be gently mixed before use