CD160 Polyclonal Antibody

CD160 Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+ CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

Immunogen Sequence:KLH conjugated synthetic peptide between 56-82 amino acids from the Central region of human CD160.

Target Alternative Name:CD160 antigen, Natural killer cell receptor BY55, CD160, CD160, BY55

Species Reactivities:Human

Tag Line:Polyclonal antibody to detect CD160 in human samples.

Formulation:PBS with 0.09% (W/V) sodium azide.

Purification: Protein A column, followed by peptide affinity purification.

Application:WB

Positive Control:WB

Application And Usages:WB: 1:1001

Handling:The antibody solution should be gently mixed before use