BCHE Antibody (Center)

BCHE Antibody (Center)is available at Gentaur for Next week Delivery.

Description: Present in most cells except erythrocytes, butyrylcholine esterase (BChE), also designated acylcholine acylhydrolase or pseudocholinesterase, has esterase activity as well as aryl acylamidase activity. It hydrolyzes acylcholine into choline and carboxylate. BChE is synthesized in the liver and is highly reactive with organophosphate esters. BChE can form a homotetramer composed of two dimers linked by a disulfide bond. Defects in the gene encoding BChE are associated with the disease hypocholinesterasemia. Inhibition of BChE effects the toxicity of organophosphates in the respiratory system suggesting that BChE may play a role in respiratory function. In addition, BChE may play an important pharmocological role by hydrolyzing toxic esters. This suggests an involvement of BChE in a treatment for intoxication with substances such as cocaine.

Immunogen Sequence:This BCHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the Central region of human BCHE.

Target Alternative Name:BCHE; CHE1; Cholinesterase; Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II; Pseudocholinesterase

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect BCHE in human samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application:Western blot

Positive Control:Western blot: A2058 cell line lysate

Application And Usages:Western blot: ~1:1000.

Handling:The antibody solution should be gently mixed before use.