ASH2 polyclonal antibody

ASH2 polyclonal antibodyis available at Gentaur for Next week Delivery.

Description: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia.

Immunogen Sequence:Polyclonal antibody raised in rabbit against mouse Ash2 (absent, small, or homeotic 2), using 3 different KLH-conjugated synthetic peptides, 2 containing an amino acid sequence from the central and 1 containing an amino acid sequence from the C-terminal part of the protein.

Target Alternative Name:ASH2L, ASH2L1, ASH2L2, Bre2

Species Reactivities:Mouse.

Tag Line:Polyclonal Antibody to detect Ash2 in mouse samples.

Formulation:In PBS with 0.05% (W/V) sodium azide.

Purification: Whole Anti-Sera

Application:Western blot, ELISA.

Positive Control:Western blot: mouse fibroblasts and neural stem cells, ELISA: Peptides, IF: NIH3T3 cells.

Application And Usages:ELISA: 1:100 – 1:500, Western Blotting: 1:500 – 1:1000, IF: 1:200.

Handling:The antibody solution should be gently mixed before use.