Artemis (DCLREIC) Antibody

Artemis (DCLREIC) Antibodyis available at Gentaur for Next week Delivery.

Description: Artemis is a 78 kDa protein, belonging to metallo-beta-lactamase superfamily. It is involved in endonuclease activity to break DNA hairpins. It also has been reported that the C-terminus of Artemis interacts with DNA binding domain of Ligase IV directly. Ligase IV is a key enzyme in DNA repair and V(D)J recombination. Thus, Artemis is a novel protein that is involved in V(D)J recombination/DNA repair. Mutations cause human T-B-severe combined immunodeficiency associated with increased cellular radiosensitivity (RS-SCID).

Immunogen Sequence:Synthetic peptide surrounding the C-terminal (BV-M21)

Target Alternative Name:DNA cross-link repair 1C protein, SNM1-like protein

Species Reactivities:Human, mouse, rat

Tag Line:Polyclonal antibody to detect Artemis in human, mouse and rat samples

Formulation:30 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2

Purification: Affinity purified

Application:Western blot

Positive Control:3T3 cell lysate

Application And Usages:Western blot: 1:200

Handling:The antibody solution should be gently mixed before use.