ApoJ/Clusterin Antibody (NT)

ApoJ/Clusterin Antibody (NT)is available at Gentaur for Next week Delivery.

Description: Native Apolipoprotein J (ApoJ), also named Clusterin, is a heavily glycosylated, 75-80 kDa disulfide-linked heterodimeric protein. Despite being cloned since 1989, no genuine function has been attributed to ApoJ so far. The protein has been reportedly implicated in several diverse physiological processes such as sperm maturation, lipid transportation, complement inhibition, tissue remodeling, membrane recycling, cell-cell and cell-substratum interactions, stabilization of stressed proteins in a folding-competent state and promotion or inhibition of apoptosis. ApoJ gene is differentially regulated by cytokines, growth factors and stress-inducing agents. Clusterin is up- or down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer, organ regeneration, infection, Alzheimer disease, retinitis pigmentosa, myocardial infarction, renal tubular damage, autoimmunity and others.

Immunogen Sequence:This CLU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human CLU.

Target Alternative Name:TRPM-2, Apolipoprotein J, APO-J, CLI, CLU, SGP-2, AAG4, KUB1, SGP2, SP-40, TRPM2, mgC24903.

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect ApoJ/Clusterin in human samples.

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Application:Western blot, IHC, FACS.

Positive Control:Western blot: A549 cell lysate, IHC: Human brain tissue, FACS: A549 cells.

Application And Usages:Western blot: ~1:1000, IHC: ~1:50-1:100, FACS: ~1:10–1:50.

Handling:The antibody solution should be gently mixed before use.