ApoA1 Antibody (NT)

ApoA1 Antibody (NT)is available at Gentaur for Next week Delivery.

Description: APOA1 promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A-I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18-amino acid signal peptide is removed co-translationally and a 6-amino acid propeptide is cleaved post-translationally. Variation in the latter step, in addition to modifications leading to so-called isoforms, is responsible for some of the polymorphism observed. APOA1 is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the C-III gene is transcribed convergent in relation to A-I. Defects in the apolipoprotein A-1 gene are associated with HDL deficiency and Tangier disease.

Immunogen Sequence:This APOA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human APOA1.

Target Alternative Name:APOA1; Apolipoprotein A-I; Apolipoprotein A1; Truncated apolipoprotein A-I; Apolipoprotein A-I(1-242)

Species Reactivities:Human

Tag Line:Polyclonal Antibody to detect ApoA1 in human samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application:Western blot, IHC

Positive Control:Western blot: HepG2 and 293 cell lysate, IHC: human placenta and hepatocarcinoma tissue

Application And Usages:Western blot: ~1:1000, IHC: ~1:10-1:50.

Handling:The antibody solution should be gently mixed before use.