Anti-WDR77 Antibody (8A10-C10-E8)

Anti-WDR77 Antibody (8A10-C10-E8)is available at Gentaur for Next week Delivery.

Description: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Immunogen Sequence:Recombinant human WDR77 protein fragments expressed in E.coli

Target Alternative Name:Methylosome protein 50, MEP-50, Androgen receptor cofactor p44, WD repeat-containing protein 77, p44/Mep50, MEP50, WD45

Species Reactivities:Human, Mouse, Rat

Tag Line:Monoclonal antibody to detect WDR77

Formulation:In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB, IF

Positive Control:WB; C6, 3T3 and K562 cell lysates, IF: HeLa cells

Application And Usages:WB; 1:1000, IF; 1:100

Handling:The antibody solution should be gently mixed before use