Anti-SMARCC1 Antibody (2A4-H7-C12)

Anti-SMARCC1 Antibody (2A4-H7-C12)is available at Gentaur for Next week Delivery.

Description: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.

Immunogen Sequence:Recombinant human SMARCC1 protein fragments expressed in E.coli

Target Alternative Name:BRG1-associated factor 155, BAF155, SWI/SNF complex 155 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect SMARCC1

Formulation:In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB

Positive Control:WB: K562, Jurkat and HeLa cell lysates

Application And Usages:WB; 1:1000

Handling:The antibody solution should be gently mixed before use