Anti-SIRT1 Polyclonal Antibody

Anti-SIRT1 Polyclonal Antibody is available at Gentaur for Next week Delivery.

Description: Sirtuin 1 (SIRT1) is an NAD-dependent protein deacetylase that links transcriptional regulation directly to myriad cellular functions such as cell cycle control, metabolism, apoptosis, and autophagy. SIRT1 can modulate chromatin function through histone deacetylation which leads to transcriptional repression of target genes. SIRT1 can also directly deacetylate transcription factors, which positively and negatively regulates target gene expression depending on the affected transcription factor. Among the proteins affected by SIRT1 are ARNTL, PER2, and CRY1, demonstrating a key role for SIRT1 in the regulation of circadian rhythm.

Immunogen Sequence:KLH-conjugated synthetic peptide of human SIRT1

Target Alternative Name:Sirtuin 1; SIR2L1; SIR2-Like Protein 1; Sirtuin Type 1; HSIRT1; HSIR2; SIR2

Species Reactivities:Rat Human

Tag Line:Coordinates cellular functions including cell cycle regulation, metabolism, apoptosis, and autophagy

Formulation:In 0.42% potassium phosphate, 0.87% NaCl, pH 7.3, w/30% glycerol and 0.01% sodium azide

Purification: Immunogen affinity chromatography

Application:Western Blotting Immunofluorescence (IF) Immunohistochemistry (IHC)

Positive Control:/

Application And Usages:Western Blotting Immunofluorescence (IF) Immunohistochemistry (IHC)

Handling:The antibody solution should be gently mixed before use.