Anti-SCGB1A1 Antibody

Anti-SCGB1A1 Antibodyis available at Gentaur for Next week Delivery.

Description: Secretoglobin family 1A member 1 (SCGB1A1, CC16, CC10, Uteroglobin) is a steroid inducible, 15.8 kDa homodimeric protein that belongs to the secretoglobin family. It is secreted in large amounts from Clara cells, which are non-ciliated cells located in the respiratory and terminal bronchioles of the lungs. It is also found in other organs such as uterus, mammary gland, prostate gland and thymus. Although the exact biological function of this protein remains elusive, SCGB1A1 has been demonstrated to have both anti-inflammatory and anti-oxidative functions. SCGB1A1 can inhibit phospholipase A2 activity, as well as modulate IFN-γ signaling and Th2 mediated inflammatory responses. Increased levels of SCGB1A1 occur in the plasma of patients suffering from pulmonary sarcoidosis, pulmonary fibrosis, or with injured lungs as a result of exposure to irritants such as asbestos, fire smoke, ozone. On the other hand, low levels of SCGB1A1 occur in the plasma of cigarette smokers and patients suffering from asthma and obliterative bronchiolitis. Therefore, SCGB1A1 could potentially serve as an efficient therapeutic target for the treatment of pulmonary diseases and injuries

Immunogen Sequence:Recombinant full length protein of human Uteroglobin

Target Alternative Name:UGB, UP1, CC10, CC16, CCSP, UP-1, CCPBP, SCGB1A1

Species Reactivities:Mouse,Human

Tag Line:Rabbit polyclonal antibody to detect SCGB1A1 expression in human and mouse samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:2000

Handling:The antibody solution should be gently mixed before use.