Anti-PTEN Rabbit Monoclonal Antibody

Anti-PTEN Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.

Description: PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling.

Immunogen Sequence:A peptide corresponding to the C-terminus of human PTEN

Target Alternative Name:Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, Phosphatase and tensin homolog, PTEN, MMAC1, TEP1, BZS, MHAM, PTEN1, 10q23del

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect PTEN in human samples.

Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: HeLa and 293 cells lysates, IHC: human brain tissue

Application And Usages:WB: 1:1000-1:2000, IHC: 1:1000-1:2000

Handling:The antibody solution should be gently mixed before use.