Anti-PPARα Polyclonal Antibody

Anti-PPARα Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: PPAR (Peroxisome proliferator-activated receptor) is a member of the nuclear hormone receptor superfamily and functions as a transcriptional activator. PPARα is preferentially expressed in liver, skeletal muscle, heart and kidney. PPARα is involved in regulation of lipid homeostasis. Its ligands include fatty acids, NSAIDs, prostaglandins, leukotriene B4, etc. PPARα transcriptionally regulates a variety of genes for enzymes and proteins involved in fatty acid metabolism and oxidation.

Immunogen Sequence:Synthetic peptide surrounding amino acid 25 of human PPARα

Target Alternative Name:PPARA , PPAR , OTTHUMP00000042872 , hPPAR , mgC2452 , OTTHUMP00000028713 , NR1C1 , PPAR-alpha , mgC2237

Species Reactivities:Human, mouse

Tag Line:Affinity purified rabbit polyclonal antibody to detect PPARα expression in human and mouse samples

Formulation:In phosphate-bufIn phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin.

Purification: Affinity purified

Application:Western blot

Positive Control:/

Application And Usages:Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~52 kDa PPARα in human sample. A ~28 kDa cleavage fragment can also be detected in samples of human, mouse, and rat origins.

Handling:The antibody solution should be gently mixed before use.