Description
Anti-phospho-Rsk1 (Thr359/Ser363), Rabbit Monoclonal Antibodyis available at Gentaur for Next week Delivery.
Description: The RSK (ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases, known also as p90(rsk). RSK1 contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. Moller described the cloning and characterization of 3 genes encoding RSKs, and HU1 (also named RPS6KA1, or RSK1) cDNA encodes a predicted 735-amino acid protein containing 2 distinct consensus ATP-binding site sequences. Northern blot and RNase protection analyses detected an approximately 3.5-kb HU1 transcript in lymphocytes, skeletal muscle, liver, and adipose tissue. Zeniou determined the expression of the RSK1, RSK2, and RSK3 genes in various human tissues, during mouse embryogenesis, and in mouse brain. RSKs are implicated in the activation of the mitogen-activated kinase (MAPK) cascade and the stimulation of cell proliferation and differentiation.
Immunogen Sequence:A phospho-peptide corresponding to human phospho-Rsk1 (Thr359/Ser363)
Target Alternative Name:rsk-1, rsk 1, Active RSK1, RSK1, RSK, human RSK1, active kinase, active kinases, recombinant RSK1, recombinant RSK, kinase activity assay, protein kinase
Species Reactivities:Human
Tag Line:Rabbit monoclonal antibody to detect phospho-Rsk1 (Thr359/Ser363) in human samples.
Formulation:In 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification: Affinity purified using protein A
Application:IHC, WB
Positive Control:WB: A431 cell lysate; IHC: human cerebral cortex tissue
Application And Usages:WB: 1:1000 - 1:2000 dilution; IHC: 1:200 -1:500 dilution
Handling:The antibody solution should be gently mixed before use.
Additional Information
Size: |
50 µl |
Antibody Target: |
RPS6KA1 |
Host: |
Rabbit |
Antibody Type: |
Monoclonal |
Isotype: |
Rabbit IgG |
Accession Number: |
Q15418 , Q15349 |
Gene Id: |
6195 , 6196 |
Appearance: |
Colorless liquid |
Form: |
Liquid |
Storage Condition: |
-20 °C |
Shipping Condition: |
gel pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
USA |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans. |
Western Blot Verified: |
Verified |
Immunocytochemistry Verified: |
Verified |
Immunofluorescence Verified: |
Not Verified |
Immunoprecipitation Verified: |
Not Verified |
FACS Verified: |
Not Verified |
ELISA Verified: |
Not Verified |
ChIP Verified: |
Not Verified |
Dot Blot Verified: |
Not Verified |
Flow Cytometry Verified: |
Not Verified |