Anti-Notch 1 (Cleaved-Val1744) Antibody

Anti-Notch 1 (Cleaved-Val1744) Antibodyis available at Gentaur for Next week Delivery.

Description: Notch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2, Notch 3 and Notch 4. The membrane ligand for Notch includes Jagged 1, Jagged 2 and Delta. Notch 1 is a 270 kDa transmembrane receptor that can be activated by Delta (Dl) ligand. Activation of Notch 1 will result in the proteolytic cleavage of Notch 1 into a 120 kDa length protein.

Immunogen Sequence:A synthesized peptide derived from human Notch 1 (Cleaved-Val1744)

Target Alternative Name:AOS5; AOVD1; hN1; Lin-12; LIN12; Mis6; Motch A; mT14; Neurogenic locus notch homolog protein 1; Neurogenic locus notch protein homolog; NICD; NOTC1_HUMAN; Notch 1; Notch 1 intracellular domain; NOTCH; Notch gene homolog 1 (Drosophila); Notch homolog 1, translocation-associated (Drosophila); NOTCH, Drosophila, homolog of, 1; notch1; TAN1; Translocation associated notch homolog; Translocation associated notch protein TAN 1; Translocation-associated notch protein TAN-1; xotch

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of Notch 1 in human samples

Formulation:In phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB, IHC, ELISA

Positive Control:WB: 3T3 cell extract, IHC: Mouse spleen tissue

Application And Usages:WB 1:500-1:2000 , IHC 1:50-1:200 , ELISA (peptide) 1:20000-1:40000

Handling:The antibody solution should be gently mixed before use.