Anti-MEK2 (KO Validated) Antibody

Anti-MEK2 (KO Validated) Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

Immunogen Sequence:Synthetic peptide derived from human MEK2

Target Alternative Name:CFC4; MAPKK2; MEK2; MKK2; PRKMK2; MAP2K2

Species Reactivities:Mouse,Human

Tag Line:Rabbit monoclonal knockout validated antibody to detect the expression of MEK2 in human and mouse samples

Formulation:In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:2000

Handling:The antibody solution should be gently mixed before use.