Anti-LRH1 Antibody

Anti-LRH1 Antibodyis available at Gentaur for Next week Delivery.

Description: Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis. Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism. Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex. Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Immunogen Sequence:Recombinant full length protein of human LRH-1

Target Alternative Name:B1F; CPF; FTF; Nuclear receptor subfamily 5 group A member 2; Alpha-1-fetoprotein transcription factor; B1-binding factor; hB1F; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1; LRH-1

Species Reactivities:Rat,Mouse,Human

Tag Line:Polyclonal antibody to detect endogenous levels of LRH1 in human, mouse and rat sample

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.

Purification: Affinity purification

Application:Immunohistochemistry (IHC),Immunofluorescence (IF),Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:2000,F/ICC 1:50 - 1:200,IHC 1:50 - 1:200

Handling:The antibody solution should be gently mixed before use.