Anti-KIAA1967 Antibody (3G4-D11-D7)

Anti-KIAA1967 Antibody (3G4-D11-D7)is available at Gentaur for Next week Delivery.

Description: Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.

Immunogen Sequence:Recombinant human KIAA1967 protein fragments expressed in E.coli

Target Alternative Name:Cell cycle and apoptosis regulator protein 2, Cell division cycle and apoptosis regulator protein 2, DBIRD complex subunit KIAA1967, Deleted in breast cancer gene 1 protein, DBC1, NET35, p30 DBC

Species Reactivities:Human, Mouse, Rat, Monkey

Tag Line:Monoclonal antibody to detect KIAA1967

Formulation:In buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol

Purification: Affinity purified

Application:WB, IF, IP

Positive Control:WB: HeLa, A549, Jurkat, C6, 3T3 and COS7 cell lysates; IF: HeLa cells; IP: HeLa cells

Application And Usages:WB; 1:1000, IF; 1:200, IP

Handling:The antibody solution should be gently mixed before use