Anti-Irisin Antibody

Anti-Irisin Antibodyis available at Gentaur for Next week Delivery.

Description: Irisin is a recently discovered exercise-induced myokine, which is secreted by skeletal muscles and produced by cleavage of the FNDC5. Studies show that Irisin stimulates mitochondria uncoupling protein-1 (UCP-1; a regulator of thermogenic capability of brown fat) expression, so Irisin can upregulate white to brown fat conversion and improve systemic metabolism by increasing energy expenditure. Hence, Irisin is a potential new drug target in the study of metabolic disorders, such as obesity and type 2 diabetes mellitus (T2DM). Moreover, FNDC5-like receptors are conserved in vertebrates and critical for neuronal development.

Immunogen Sequence:Human recombinant Irisin

Target Alternative Name:Fibronectin Type III Domain-containing Protein 5, FNDC5 (cleaved); Fibronectin Type III Repeat-containing Protein 2, FRCP2 (cleaved)

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal Antibody to detect Irisin in human, mouse and rat samples

Formulation:In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% Proclin

Purification: Affinity purified

Application:WB

Positive Control:WB: Rat kidney lysate, Human recombinant Irisin

Application And Usages:WB: 1-4 µg

Handling:The antibody solution should be gently mixed before use.