Anti-IMP3 Antibody (1F1-E10-D11)

Anti-IMP3 Antibody (1F1-E10-D11)is available at Gentaur for Next week Delivery.

Description: RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Immunogen Sequence:Recombinant human IMP3 protein fragments expressed in E.coli

Target Alternative Name:Insulin-like growth factor 2 mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IMP-3, IGF-II mRNA-binding protein 3, KH domain-containing protein overexpressed in cancer, hKOC, VICKZ family member 3

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect IMP3

Formulation:In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB

Positive Control:WB: MCF7, SKVO3, NTERA2, Jurkat, Hela and K562 cell lysates

Application And Usages:WB; 1:1000

Handling:The antibody solution should be gently mixed before use