Anti-EHMT2 Antibody

Anti-EHMT2 Antibodyis available at Gentaur for Next week Delivery.

Description: G9a, also known as Euchromatic histone-lysine N-methyltransferase 2 (EHMT2), is a member of a family of histone lysine methyltransferases, each of which contains a conserved catalytic SET domain originally identified in Drosophila Su[var]3-9, Enhancer of zeste, and Trithorax proteins. Recombinant G9a can mono-, di- and tri-methylate histone H3 on Lys9 and Lys27 in vitro. However, in vivo G9a forms a complex with GLP, a G9a-related histone methyltransferase, and together these proteins function as the major euchromatic histone H3 Lys9 mono- and di-methyltransferases, creating transcriptionally repressive marks that facilitate gene silencing. G9a methylates itself on Lys165, a modification that regulates the association of HP1 repressor proteins with the G9a/GLP complex.

Immunogen Sequence:A synthesized peptide derived from human EHMT2

Target Alternative Name:BAT8; C6orf30; G9A; KMT1C; NG36; Histone-lysine N-methyltransferase EHMT2; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9a

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of EHMT2 in human, mouse and rat samples

Formulation:In phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB, IHC

Positive Control:WB: HeLa cell lystae, IHC: Mouse liver tissue

Application And Usages:WB 1:500-1:2000, IHC 1:50-1:200

Handling:The antibody solution should be gently mixed before use.