Anti-Dopamine beta-Hydroxylase Antibody

Anti-Dopamine beta-Hydroxylase Antibodyis available at Gentaur for Next week Delivery.

Description: The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neurosecretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders.

Immunogen Sequence:KLH-conjugated synthetic peptide targeting a sequence within the center region of human Dopamine beta-Hydroxylase

Target Alternative Name:Dopamine beta-hydroxylase; Dopamine beta-monooxygenase

Species Reactivities:Mouse, Human

Tag Line:Affinity purified rabbit polyclonal antibody to detect Dopamine beta-Hydroxylase expression in human and mouse samples

Formulation:In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:Western Blotting

Positive Control:/

Application And Usages:WB 1:500 - 1:1000

Handling:The antibody solution should be gently mixed before use.