Anti-DCTN1 Antibody (3D5-C6-D5)

Anti-DCTN1 Antibody (3D5-C6-D5)is available at Gentaur for Next week Delivery.

Description: Plays a key role in dynein-mediated retrograde transport of vesicles and organelles along microtubules by recruiting and tethering dynein to microtubules. Binds to both dynein and microtubules providing a link between specific cargos, microtubules and dynein. Essential for targeting dynein to microtubule plus ends, recruiting dynein to membranous cargos and enhancing dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). Can also act as a brake to slow the dynein motor during motility along the microtubule.

Immunogen Sequence:Recombinant human DCTN1 protein fragments expressed in E.coli

Target Alternative Name:Dynactin subunit 1, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p135, p150-glued

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect DCTN1

Formulation:In PBS (pH 7.4) containing with 0.02% sodium azide and 50% glycerol

Purification: Affinity purified

Application:WB

Positive Control:WB: K562, MCF7, 293T and HeLa cell lysates, IP: HeLa cells

Application And Usages:WB; 1:500

Handling:The antibody solution should be gently mixed before use