Anti-Citrullinated Myelin Basic Protein Polyclonal Antibody

Anti-Citrullinated Myelin Basic Protein Polyclonal Antibodyis available at Gentaur for Next week Delivery.

Description: Myelin basic protein (MBP) comprises several isoforms of a single gene product, which together make up a major component of the myelin sheath of oligodendrocytes and Schwann cells in the central nervous system. MBP contains 19 arginine residues that can be citrullinated by protein arginine deiminases (PADs), which will decrease the positive charge of the protein. The decrease in positive charge disrupts MBP interactions with the lipid membranes of myelin sheath cells. Citrullinated MBP is associated with demyelination and multiple sclerosis.

Immunogen Sequence:Synthetic peptide derived from human myelin basic protein (isoform 5) citrullinated at R122 and R130

Target Alternative Name:Myelin Membrane Encephalitogenic Protein; Myelin A1 Protein; Proline-Rich Proteoglycan 2; Golli-MBP; MBP

Species Reactivities:Human

Tag Line:An autoimmune biomarker in multiple sclerosis

Formulation:PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide

Purification: Peptide affinity purification

Application:ELISA Western Blotting

Positive Control:/

Application And Usages:/

Handling:The antibody solution should be gently mixed before use.