Anti-CD86 Antibody (Clone C86/1146)

Anti-CD86 Antibody (Clone C86/1146)is available at Gentaur for Next week Delivery.

Description: This antibody recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.

Immunogen Sequence:Recombinant human full-length CD86 protein

Target Alternative Name:Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2, B70, BU63, CD86, CD28LG2

Species Reactivities:Human, Mouse and Rat

Tag Line:Monoclonal Antibody to detect CD86 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, WB, IHC

Positive Control:IHC: human Melanoma, FC: human PBMC's , WB: Daudi Cell Lysate

Application And Usages:FC: 0.5-1 µg/1X106 cells in 0.1 ml, IF: 0.5-1 µg/ml, WB: 0.5-1 µg/ml, IHC: 2-4 µg/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use