Anti-CD6 (Itolizumab), Humanized Antibody

Anti-CD6 (Itolizumab), Humanized Antibodyis available at Gentaur for Next week Delivery.

Description: The research-grade biosimilar is a humanized recombinant IgG1 monoclonal antibody that specifically targets the scavenger receptor cysteine-rich (SRCR) distal domain 1 of CD6. CD6 is a co-stimulatory molecule that is primarily expressed on the T-cell surface and plays an important role in the maturation, activation, and differentiation of T-cells, and pro-inflammatory cytokine production. Binding of Itolizumab to CD6 prevents T-cell activation, decreases the levels of IFN-γ, IL-6, and TNF-α and thus reduces inflammation. The original drug was approved by the DCGI in India to treat moderate-to-severe plaque psoriasis. In 2020, the drug received approval to treat moderate-to-severe COVID-19 complications.

Immunogen Sequence:Human CD6

Target Alternative Name:T1h, XQQ2RHV14N, TP120, T12

Species Reactivities:Human

Tag Line:The biosimilar is a humanized monoclonal antibody that targets CD6 and inhibits T-cell activation and thus reduces inflammation

Formulation:In PBS, pH 7.5

Purification: Protein A purified

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Handling:The antibody solution should be gently mixed before use.