Anti-CD34 Antibody (QBEnd/10)

Anti-CD34 Antibody (QBEnd/10)is available at Gentaur for Next week Delivery.

Description: This mAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. On the basis of differential sensitivity to degradation by specific enzymes, epitopes of monoclonal antibodies to CD34 are classified into a three main categories, class I, class II and class III. It is a class II antibody whose epitope is resistant to neuraminidase but sensitive to glycoprotease and chymopapain. CD34 expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and Kaposi’s sarcoma, but with a lower specificity.

Immunogen Sequence:Detergent solubilized vesicular suspension prepared from human term placenta

Target Alternative Name:Hematopoietic Progenitor Cell Antigen, HPCA1, Mucosialin

Species Reactivities:Human, Cynomolgus Monkey, Rhesus Monkey

Tag Line:Monoclonal Antibody to detect CD34 in human, Cynomolgus Monkey, Rhesus Monkey samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Tonsil

Application And Usages:FC: 0.5-1ug/1X106 cells in 0.1ml, IF: 0.5-1ug/ml, IHC: 0.25-0.5ug/ml for 30 minutes at RT

Handling:The antibody solution should be gently mixed before use