Description
Anti-CD20 / MS4A1 Antibody (SPM618)is available at Gentaur for Next week Delivery.
Description: Recognizes a protein of 30-33kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This mAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.
Immunogen Sequence:Recombinant human MS4A1 protein
Target Alternative Name:APY; ATOPY; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; Bp35; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; Leukocyte surface antigen Leu-16; Ly44; Membrane spanning 4 domains subfamily A member 2; Membrane-spanning 4-domains subfamily A member 1 (MS4A1)
Species Reactivities:Human
Tag Line:Monoclonal Antibody to detect CD20/MS4A1 in human samples
Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification: Protein A/G purification
Application:FC, IF, IHC
Positive Control:IHC: human Tonsil
Application And Usages:FC: 0.5-1 ug/1X106 cells in 0.1ml, IF: 0.5-1 ug/ml, IHC: 0.5-1 ug/ml
Handling:The antibody solution should be gently mixed before use
Additional Information
Size: |
100 µg |
Antibody Target: |
CD20/MS4A1 |
Category: |
Immunology |
Lot Number: |
N/A |
Host: |
Mouse |
Antibody Type: |
Monoclonal |
Isotype: |
Mouse / IgG2a, kappa |
Accession Number: |
P11836 |
Gene Id: |
931 |
Appearance: |
Colorless liquid |
Form: |
Liquid |
Storage Condition: |
-20 °C |
Shipping Condition: |
gel pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
USA |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans |
Western Blot Verified: |
Not Verified |
Immunocytochemistry Verified: |
Verified |
Immunofluorescence Verified: |
Not Verified |
Immunoprecipitation Verified: |
Not Verified |
FACS Verified: |
Not Verified |
ELISA Verified: |
Not Verified |
ChIP Verified: |
Not Verified |
Dot Blot Verified: |
Not Verified |
Flow Cytometry Verified: |
Not Verified |