Anti-CD1b Antibody (RIV12)

Anti-CD1b Antibody (RIV12)is available at Gentaur for Next week Delivery.

Description: The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.

Immunogen Sequence:Human peripheral lymphocytes

Target Alternative Name:A1 domain; CD1B; Cortical thymocyte antigen CD1B; hTa1 thymocyte antigen; Ly38; T cell surface glycoprotein CD1b; T6/Leu6

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD1b in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF

Positive Control:IHC: human PBMC's

Application And Usages:FC: 0.5-1 ug/1X106 cells in 0.1ml, IF: 0.5-1 ug/ml

Handling:The antibody solution should be gently mixed before use