Anti-CD162 Antibody (PSGL1/1601)

Anti-CD162 Antibody (PSGL1/1601)is available at Gentaur for Next week Delivery.

Description: CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

Immunogen Sequence:Recombinant human full-length SELPLG (CD162) protein

Target Alternative Name:CD162; CLA; Cutaneous lymphocyte associated antigen; P-selectin glycoprotein ligand 1; PSGL1; Selectin P ligand; SELPLG

Species Reactivities:Human

Tag Line:Monoclonal Antibody to detect CD162 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC

Positive Control:IHC: human Spleen, human Tonsil

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml, IHC: 1-2 ug/ml

Handling:The antibody solution should be gently mixed before use