Anti-Bcl-2 Antibody (100/D5 + 124)

Anti-Bcl-2 Antibody (100/D5 + 124)is available at Gentaur for Next week Delivery.

Description: This antibody recognizes a protein of 25-26 kDa, identified as the bcl-2 α oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2 α oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2 α protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.

Immunogen Sequence:A synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2

Target Alternative Name:Apoptosis regulator Bcl-2, B-cell CLL/lymphoma-2

Species Reactivities:Human

Tag Line:Monoclonal antibody to detect Bcl-2 in human samples

Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide

Purification: Protein A/G purification

Application:FC, IF, IHC, WB

Positive Control:IHC: human non-Hodgkin's Lymphoma, FC: Jurkat cells, WB: human skin lysate

Application And Usages:FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml, WB: 0.5-1ug/ml, IHC: 0.5-1 ug/ml

Handling:The antibody solution should be gently mixed before use.