Anti-Angiopoietin-2 Antibody

Anti-Angiopoietin-2 Antibodyis available at Gentaur for Next week Delivery.

Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.

Immunogen Sequence:KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Angiopoietin-2

Target Alternative Name:Angiopoietin-2, ANG-2

Species Reactivities:Human, Mouse, Rat

Tag Line:Polyclonal antibody to detect endogenous levels of ANGPT2 in human, mouse and rat samples

Formulation:In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application:WB

Positive Control:WB: Hela, Raw264.7, H9C2 whole cell lysate

Application And Usages:WB; 1:500 – 1:1000

Handling:The antibody solution should be gently mixed before use