Description
Anti-AMACR / p504S Antibody (AMACR/1723)is available at Gentaur for Next week Delivery.
Description: This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
Immunogen Sequence:Recombinant human full-length AMACR protein
Target Alternative Name:Alpha-methylacyl-CoA Racemase, CBAS4, Da1-8, Macr1, RACE, RM
Species Reactivities:Human
Tag Line:Monoclonal antibody to detect AMACR in human samples
Formulation:In 10 mM PBS with 0.05% BSA & 0.05% azide
Purification: Protein A/G purification
Application:IF, IHC
Positive Control:IHC: human prostate carcinoma
Application And Usages:IF: 1-2 ug/ml, IHC: 1-2 ug/ml
Handling:The antibody solution should be gently mixed before use.
Additional Information
Size: |
100 µg |
Antibody Target: |
AMACR |
Category: |
Marker antibody |
Lot Number: |
N/A |
Host: |
Mouse |
Antibody Type: |
Monoclonal |
Isotype: |
Mouse IgG |
Accession Number: |
Q9UHK6 |
Gene Id: |
23600 |
Appearance: |
Colorless liquid |
Form: |
Liquid |
Storage Condition: |
-20°C |
Shipping Condition: |
gel pack |
Shelf Life: |
12 months |
Country of Animal Origin: |
USA |
Country of Manufacture: |
USA |
Usage: |
For Research Use Only! Not to be used in humans. |
Western Blot Verified: |
Not Verified |
Immunocytochemistry Verified: |
Verified |
Immunofluorescence Verified: |
Not Verified |
Immunoprecipitation Verified: |
Not Verified |
FACS Verified: |
Not Verified |
ELISA Verified: |
Not Verified |
ChIP Verified: |
Not Verified |
Dot Blot Verified: |
Not Verified |
Flow Cytometry Verified: |
Not Verified |