Anti-5-Hydroxymethylcytosine Antibody

Anti-5-Hydroxymethylcytosine Antibodyis available at Gentaur for Next week Delivery.

Description: 5-hydroxymethylcytosine (5-hmC) is a modified base form of cytosine recently found in human/mouse brain and in embryonic stem cells. This DNA pyrimidine nitrogen base can be generated by oxidation of 5-methylcytosine, a reaction mediated by the ten-eleven translocation (TET) family of the 5-mC hydroxylases. The function of this base is still not elucidated but it is believed to play an important role in switching genes on and off.

Immunogen Sequence:5-hydroxymethylcytosine (5-hmC) is a modified base form of cytosine recently found in human/mouse brain and in embryonic stem cells. This DNA pyrimidine nitrogen base can be generated by oxidation of 5-methylcytosine, a reaction mediated by the ten-eleven translocation (TET) family of the 5-mC hydroxylases. The function of this base is still not elucidated but it is believed to play an important role in switching genes on and off.

Target Alternative Name:5-hmc, 5hmc

Species Reactivities:Human, Mouse, Rat

Tag Line:Monoclonal antibody to detect 5-Hydroxymethylcytosine

Formulation:Phosphate Buffer 10mM - NaCl 0.15 M - pH 7.5

Purification: Affinity purified

Application:ELISA, hMeDIP IF, Dot Blot

Positive Control:Dot Blot, ELISA

Application And Usages:ELISA: 1:1000, hMeDIP: 1-3 µg per IP, IF: 1:500, Dot Blotting: 1:2,000

Handling:The antibody solution should be gently mixed before use