ANGPTL1 Antibody (NT)

ANGPTL1 Antibody (NT)is available at Gentaur for Next week Delivery.

Description: Angptl1 (angiopoietin-like 1), also known as angioarrestin, ARP1, ANGPT3 or previously known as angiopoietin 3 (ANG3), is a member of the angiopoietin-like family. It is highly expressed in adult tissues, particularly adrenal gland, thyroid, placenta and small intestine. Angptl1 exists as a disulfide-linked dimer and shares 45.1% identity with Ang-1 and 59% identity with Angptl2. Angptl1 consists of an N-terminus with a coiled-coil domain, potential glycosylation sites and a C-terminus with a fibrinogen-like domain. It is a secreted protein but does not function as a growth factor in endothelial cells. Angptl1 plays a distinct role in the regulation of angiogenesis; inhibiting proliferation, migration, tube formation and endothelial cell adhesion. To exert this inhibitory activity, Angptl1 is speculated to interact with a receptor on endothelial cells. In a wide variety of tumor tissues, Angptl1 expression is down-regulated suggesting that a major function of this protein involves its antiangiogenic properties.

Immunogen Sequence:This ANGPTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-44 amino acids from the N-terminal region of human ANGPTL1.

Target Alternative Name:ANGPTL1; ANG3; ANGPT3; ARP1; Angiopoietin-related protein 1; Angiopoietin-3; Angiopoietin-like protein 1

Species Reactivities:Human.

Tag Line:Polyclonal Antibody to detect ANGPTL1 in human samples.

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Application:Western blot, IHC, FACS.

Positive Control:Western blot: HeLa cell lysate, IHC: Human placenta tissue, FACS: HeLa cells.

Application And Usages:Western blot: ~1:1000, IHC: ~1:50-1:100, FACS: ~1:10–1:50.

Handling:The antibody solution should be gently mixed before use.