AKR7A2 Antibody (NT)

AKR7A2 Antibody (NT)is available at Gentaur for Next week Delivery.

Description: The aldo-keto reductase 7 (AKR7) family includes AKR7A2, AKR7A3 and AKR7A4 in human, AKR7A5 in mouse and AKR7A2 in rat, all of which function in the metabolism of aflatoxin B(1) and other dicarbonyl-containing compounds. More specifically, AKR7A proteins are involved in the metabolism of compounds with ketone groups on adjacent carbon atoms in a broad range of tissues, notably the liver. The human AKR7A2 gene maps to human chromosome 1p35-36, a region frequently deleted in sporadic colorectal cancer. The functional significance of this correlation lies in the constitutive expression of AKR7A2 in human liver to eliminate aflatoxin (an environmental carcinogen), thus acting as an endogenous chemo-preventative agent.

Immunogen Sequence:This AKR7A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-129 amino acids from the N-terminal region of human AKR7A2.

Target Alternative Name:AKR7A2; AFAR; AFAR1; AKR7; Aflatoxin B1 aldehyde reductase member 2; AFB1 aldehyde reductase 1; Aldoketoreductase 7; Succinic semialdehyde reductase.

Species Reactivities:Human and mouse. Predicted cross reactivity with rat samples.

Tag Line:Polyclonal Antibody to detect AKR7A2 in human and mouse samples

Formulation:100 µl of antibody in PBS with 0.09% (W/V) sodium azide

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application:Western blot.

Positive Control:Western blot: 293 cell lysates.

Application And Usages:Western blot: ~1:1000.

Handling:The antibody solution should be gently mixed before use.